Mosegor: Anti-Migraine Drug
Mosegor has been known as an appetite stimulant. Interestingly, as a pizotifen, it can also be indicated for migraine headaches.
- Mosegor facts
- Side effects and drug interactions
- Mosegor: Anti-migraine Drug
Mosegor is prescription drug manufactured by Sandoz in the Philippines and by Novartis in Thailand. It is available as a 0.5 mg tablet.
As a Pizotifen hydrogen maleate, Mosegor is classified as an antihistamine or anti-serotonin agent. It is a prophylactic migraine drug that works like a calcium channel blocker. It hinders the contraction in the arteries induced by serotonin- a neurotransmitter that controls pain.
For the elderly, pizotifen is to be given at night with the initial dose of 0.5 mg (500mcg). But if this dosage regimen doesn’t work, the dose is gradually increased to three times daily. Maximum dose for adult as a single dose is 3 mg and 4.5 mg in divided doses.
For children 6 to 12 years old, starting dose is 500mcg to 1mg doses. Daily doses up to a maximum of 1.5mg should be given two to three divided doses.
In children from 6 years of age, a maximum single dose of 1mg can be given at night.
Mosegor is contraindicated with individuals who have hypersensitivity to the drug, those with glaucoma and prostatic hypertrophy - an overgrowth or enlargement of prostate glands in males.
Mosegor should be used in precaution in people with renal problems; in patients with history of epilepsy; in cases of urinary retention and in pregnant women. The concentrations of pizotifen in milk does not likely to affect the infant, but its use in nursing mothers is still not recommended.
Side effects and drug interactions
Common side effects are sedation, nausea, dryness of mouth and weight gain.
Sedation may also be enhanced by sedatives, alcohol, antihistamines and cold preparations with antihistamines
Mosegor: Anti-migraine Drug
As a prophylactic medication, Mosegor can reduce the occurrence and period of migraine headaches but will not eliminate the condition. Although it can be an effective choice as prevention for migraine without the unpleasant side effect of heaviness, stomach upsets or liver problems, its use is still limited because of its untoward reactions as drowsiness and weight gain.
With this, other prophylactic migraine drugs which include the cyclandelate, valproic acid, magnesium, the antidepressant amitriptyline, beta blockers propranolol and the calcium channel blocker verapamil are used in place of this drug. Mosegor is not effective in relieving a migraine attack once in progress of if the pain has already begun.
© Phoenix Montoya @ June 6, 2011